Aslam M, Rehan Asif Siddiqui, Naseem A Khan.
Central Neurotoxicity of Gentamicin: Gentamicin induced `In Vitro` Mg2+ dependent ATPase activity in auditory area of rat brain.
Pak J Otolaryngol Jan ;18(3):41-2.

The exact mechanism of otoneurotoxicity of gentamicin is unknown. A study was carried out on the auditory cortex of rat brain both `in vitro` and `in vivo` following the administration of gentamicin 135 mglkg body weight for 21 days. Interestingly, the Mg2+ dependent ATPase was increased following the intoxication of gentamicin.

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