Shama Bai, Syed Fasih Ahmed Hashmi.
Association between helicobacter pylori infection and acute myocardial infarction (ami).
Pak Heart J Jan ;50(1):33-8.

Objective: To determine the association between helicobacter pylori infection and acute myocardial infarction. Methodology: A six months case-control study was conducted at Cardiology Department of Liaquat Medical University Hospital, Jamshoro. The study comprised of patients presenting with acute myocardial infarction (cases) admitted with myocardial injury and controls that were volunteer individuals. The relevant laboratory investigations were advised and the data was analyzed using SPSS version 22.0. Results: Total 218 individual were evaluated. Of them 109 (50%) were controls and 109 (50%) were cases during study period. About 110 (50.45%) participants were males. The mean age of controls was 51.88+-.7.90 years and cases 50.93+-8.13 years with range of 35-65 (t= -.870, p=.385). H-Pylori status was positive in 75.2% of cases as compared to 41.2% of controls ( 2=5.945,p=.001). Also higher in males 85.4% than females (t=7.348 and p=.000). Conclusion: It was concluded that H-Pylori infection was significantly associated with patients compared to controls. Therefore,monitoring of H-Pylori infection as a possible risk factor of coronary artery disease may be of clinical value.

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