Badar-ul Ahad Gill, Tariq Mehmood Khan, Muhammad Tahir Mohyuddin, Tariq Abbas, Zahid Rafique Butt, Bilal Ahsan Qureshi, Ijaz Ahmed.
Diagnostic accuracy of single photon emission computed tomography by taking coronary angiography as gold standard for the detection of coronary artery disease.
Pak Heart J Jan ;49(1):40-3.
Objective: To determine the diagnostic accuracy of Single Photon Emission Computed Tomography by taking Coronary Angiography as gold standard for the detection of Coronary Artery Disease. Methodology: It is a cross-sectional study conducted at the Department of Cardiology, Chaudhry Pervaiz Elahi Institute of Cardiology, Multan from September 2013 to March 2014. Patients with age 40 years belonging to either sex with at least one episode of chest pain lasting for 30 minutes were included in the study. All patients underwent SPECT Scan and the findings of SPECT were confirmed by performing Coronary Angiography of every patient. Results: Out of 282 patients, 45.03%(n=127) were between 40-60 years and 54.97%(n=155) had >60 years of age, with mean age of 60.83+-9.32 years.Males were 52.13%(n=147). Results of single photon emission computed tomography by taking coronary angiography as gold standard for the detection of coronary artery disease showed 17.02%(n=48) were true positive, 2.48%(n=7) were false positive, 77.31% (n=218) were true negative and 3.19%(n=9) were false negative. Sensitivity, specificity, positive predictive value,negative predictive value and accuracy rate was computed as 84.21%, 96.88%,87.27%, 96.03% and 94.33% respectively. Conclusion: We concluded that Single Photon Emission Computed Tomography,by taking Coronary Angiography as gold standard for the detection of Coronary Artery Disease, has a good diagnostic accuracy and can be used to curtail the financial burden of diagnosis.
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