Muzaffar Ali, Usman Mahmood Butt, Zubair Akram.
Immediate outcomes of percutaneous transvenous mitral commissurotomy of patients with severe mitral stenosis in different age groups.
Pak Heart J Jan ;48(4):211-4.

Objectives: To evaluate the immediate outcomes of PTMC for severe mitral valve stenosis. Methodology: This cross sectional study was conducted from January 2015 to December 2015 at Cardiology Department Jinnah hospital Lahore. Patients with severe mitral valve stenosis having Mitral valve area (MVA) 1.0 cm who underwent PTMC with suitable valve morphology. All patients underwent PTMC using the trans-septal antegrade technique, after informed consent was obtained. Echocardiography was performed in all patients before and after PTMC to assess the severity of mitral regurgitation. Patients were divided in two groups based on younger < 35 years and older age (36 - 60 y) and comparison was made to assess difference before and after intervention. Independent t-test and Chi-square test was used to assess difference in severity of Mitral stenosis before and after PTMC in different age groups with p<0.05 as statistical significant. Results: A total of 60 subjects with severe mitral stenosis underwent PTMC. Mean age was 29.98 +- 10.824 years.The younger group <35 years were 68.3% and 31.7% were older between 36-60 years. There were 88.3% female. Mean pre and post PTMC MVA was 0.83+-0.133 and 1.53+-0.383 cm (t=2.172 p< .034) respectively. Similarly mean pre and post PTMC MVPG was 27.20 +-6.802 and 12.88+-6.3813 (t=4.591 p<.000). The success rate of the PTMC was significantly higher among 10-35 years 87.8% than 36-60 years 52.7 % (X=8.979 p =.003). Conclusion: PTMC is a safe and effective treatment for patients with severe MS who have suitable valve morphology especially in younger age.

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