Lachman Das, Nandlal Rathi, Alvina Munaf, Muhammad Zaman Baloch, Jawad Rafique Arain, Bhunesh Maheshwari, Komal Lohana, Feroz Memon.
Impact of combined white blood cell count and plasma glucose for predicting in-hospital outcomes after acute myocardial infarction.
Pak Heart J Jan ;47(3):151-5.

Objective: To determine the combined effects of WBC count and Plasma Glucose levels on predicting in-hospital outcomes in patients with acute myocardial infarction. Methodology: This cross-sectional study was conducted at Liaquat University of medical and health sciences Hyderabad between the periods of 12 months (1 st January 2011 to 31 st December 2011). All consecutive patients with acute myocardial infarction with age >= 18 years of either sex were included. White blood cell count and plasma glucose levels were measured and compared their relationship with in-hospital mortality rates. SPSS version 16 was used for data entrance and analysis. A p value of <0.05 were considered statistically significant. Results: Among 916 patients, the mean age of the patients +- standard deviation was 60 +- 2 years with predominant male proportion (74%). Majority of them (60%) were diagnosed as acute anterior wall myocardial infarction. Overall in-hospital mortality rate was 109 (12%). In-hospital mortality rate was significantly higher observed in patients with a higher count of WBC and elevated levels of plasma glucose (p<0.05). Conclusion: Patients with hyperglycemia and raised WBC count at the time of hospitalization with acute myocardial infarction had an increased in-hospital mortality rate. A step wise increase in peak creatinine kinase level and a step wise decrease in left ventricular ejection fraction were also observed in patients with high PG levels with high WBC count.

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