Lubna Noor, Yasir Adnan, Mohammad Faheem, Shahab-ud Din, Amina Amina, Kamran Bangash, Zahid Aslam Awan.
Clinical profile of arrhythmogenic right ventricular cardiomyopathy (ARVC).
Pak Heart J Jan ;47(3):145-50.

Objective: To study the clinical profile of patients with ARVC in the province of Khyber Pakhtunkhwa (KP). Methodology: This prospective observational study was carried out at the department of Cardiology in Hayatabad Medical Complex, PGMI, Peshawar from April, 2008 to March, 2011. The Task Force Criteria 2004 was employed to iagnose the patients. Clinical data of the patients including age, gender, family history, presenting symptoms, twelve lead resting ECG, 24-hours ECG Holter monitoring, signal-average ECG, 2-dimensional transthoracic echo and right ventriculograms were analyzed. Result: Twenty-eight patients, fulfilling the diagnostic criteria, were included.The mean age at clinical presentation was 30.22+-11.88 (range 18 to 42 years),with a male: female ratio of 3.66:1. Twenty-six (92%) presented with VT of LBBB morphology, all patients (100%) had history of palpitations, and 7 patients (25%)had positive family members as well. Various ECG findings were found in 42 to 96% of the patients, SAECG showed late potentials in 12% of the patients, and Holter monitoring yielded various findings in 67 to 92% of the patients. Among imaging modalities, 2-D echo picked up positive findings in 3.5 to 85% of the patients, while RV-gram was helpful in 25 to 46% of the patients. Conclusion: ARVC mostly presents either with palpitations or VT of LBBB morphology. 12 lead resting ECG and 2-D transthoracic echo are mostly helpful in the diagnosis.

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