Jaan Muhammad, Naveed Akhtar, Muhammad Khurram Ahmad, Muhammad Irfan Anwar.
Comparison of efficacy between intralesional bleomycin and cryotherapy in plantar warts.
J Pak Assoc Derma Jan ;29(1):35-9.

Objective To compare the efficacy of intralesional bleomycin and cryotherapy in treating plantar warts. Material and Methods A total of 160 patients (80 in each group) were enrolled, who were randomly divided into 2 groups. Group A was treated with 0.1% intralesional bleomycin and group B was treated with liquid nitrogen with a cotton swab. Follow-up was carried out at 02, 04 and 06 weeks and the final efficacy was calculated at the end of 06 weeks. Results Out of 160 patients, 32 (40.0%) male and 48 (60.0%) female were enrolled in intralesional bleomycin group; 30(36.5%) male and 50 (62.5%) females were included in cryotherapy group. Mean±SD of age in intralesional bleomycin and cryotherapy was 28.24±4.2 with C.I (27.30-29.17) and 27.56±3.8 with C.I (26.71-28.40) years, respectively. In comparison of both groups 90% efficacy was found in intralesional bleomycin group whereas 72.5% in cryotherapy group and p value was found to be highly significant i.e. (P=0.005). Conclusion Intralesional bleomycin is more effective than cryotherapy in the treatment plantar warts.  

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