Nadhir Zafar Khan, Muhammad Naeem Kasuri, Azim Taj, Tafazule Haque Mahmud, Zafar Iqbal.
Sensory abnormalities on Nerve Conduction Studies in patients with Acute Idiopathic Polyradiculoneuropathy.
Ann King Edward Med Uni Jan ;9(2):160-2.

Acute Idiopathic Polyradiculoneuropathy (AIP) is a potentially fatal acute polyneuropathy characterized by ascending muscle weakness and is the most common cause of hospital admission due to acute motor polyneuropathy. This study was done to see sensory changes on nerve conduction studies in patients with AIP. Seventy eight patients diagnosed as AIP on nerve conduction studies and electromyography were selected for the study that was conducted at Shaikh Zayed Hospital and Mayo Hospital Lahore. The patients were classified into demyelinating, acute motor axonal neuropathy (AMAN), acute sensory and motor axonal neuropathy (ASMAN) and mixed variety of AIP based on electrodiagnostic studies. Sensory changes predominantly of axonal type were observed in 87% cases of demyelinating variety of AIP. All cases of AMAN had normal sensory nerve condcution studies while 5 out of 6 cases of ASMAN and 7 out of 8 cases of mixed variety of AIP also predominantly. axonal sensory damage. As the predominant sensory nerve damage was axonal in demyelinating type of AIP, there may be different pathological mechanism responsible for sensory nerve damage which requires further research for proper understanding of pathological process.

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