Muzaffar Ali, Usman Mahmood Butt, Umer Aftab.
Association of waist-hip ratio with severity of coronary artery disease in patients undergoing coronary angiogram for acute coronary syndrome.
Pak Heart J Jan ;51(3):238-42.

Objectives: To determine the association of increased waist-hip ratio with severe coronary artery disease. Methodology: This case control study was conducted at Department of Cardiology, Jinnah Hospital, Lahore from 13th December 2014 to 12th June 2015.Male shaving coronary artery disease (stenosis of > 50% in a major epicardial coronary artery) were included in the study and waist-hip ratio was determined at the time of inclusion into study. Matched controls were taken from same population. Waist-hip ratio of more than 0.95 was taken as increased waist-hip ratio. Odds ratio was calculated to determine the association of increased waist hip ratio with severe coronary artery disease. Results: A sample of 360 including 180 in each cases and control groups were included with mean age of 41.62 +- 2.749 ranging from 35 to 45 years of age.Odds ratio (OR) for increased Waist/Hip ratio>0.95 among cases and controls was 1.93 (p < 0.028). Stratification of Waist/Hip ratio > 0.95 with current smokers, 147 (88.6%) among cases were currently smoking with Waist / Hip ratio > 0.95 and 134 (8.2%) among controls that were currently smoking had Waist / Hip ratio>0.95. (OR=1.905, p=0.037). Conclusion: The study concluded that coronary heart disease risk increases with increase waist/hip ratio and is further augmented by smoking. Key Words: Coronary artery disease, Myocardial infarction,Waist/Hip ratio.

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