Syed Nauman Ali, Hamza Ghafoor, Kashif Ali Hashmi, Mubasher Ali Khan Sherwani.
Coronary artery disease in premenopausal women.
Pak Heart J Jan ;52(1):52-7.

Objective: To determine the frequency of coronary artery disease in premenopausal women. Methodology: This cross sectional study included premenopausal women (aged 18-40 years) of any parity presenting in Cardiology Emergency Department of Chaudry Pervaiz Elahi Institute of Cardiology, Multan, from 26 July to 25th November 2018, were included in the study by non probability, consecutive sampling with chest pain and breathlessness were included in this study. These patients received standard cardiac care and underwent coronary angiography where diagnosis of CAD was confirmed. Results: Total of 375 patients were included. Coronary artery disease (CAD) was diagnosed in 147 (39.20%) patients on coronary angiography (CAG). Diabetes was diagnosed in 81 (59.6%) patients having CAD and in 55 (40.4%) patients without CAD (p<0.0001). Hypertension was diagnosed in 89 (50.6%) patients with CAD and in 58 (29.1%) patients without CAD (p<0.0001). Mean triglycerides in CAD patients was 1.82+0.52 mmol/L versus 1.41+-0.52mmol/L in non-CAD patients (p<0.0001). Conclusion: There is a high prevalence of coronary artery disease in symptomatic pre-menopausal women. Diabetes, hypertension and elevated serum triglyceride levels are associated with higher prevalence of CAD.

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