Areeba Riaz, Muhammad Imran Hanif, Iqra Hamid Khan, Asif Hanif.
Frequency and causes of periprocedural myocardial infarction in complex coronary interventions.
Pak Heart J Jan ;52(2):137-43.

Objective: To examine the frequency and cause sof periprocedural myocardial infarction (PMI) in complex coronary interventions. Methodology: This cross sectional study was conducted at catheterization laboratory of Gulab Devi Chest Hospital, Lahore in 6 months duration from June 2016 to January 2017. Patients aged between 30 to 80 years undergoing complex coronary interventions were included. Blood samples for creatine kinase-MB evaluation were drawn at three different times i.e. Once before procedure, 8-10 and 24 hours after the procedure. CKMB level >3+- ULN was considered as PMI. Association of different factors with PMI was also observed. Results: A total of 72 consecutive patients were included in the study.Mean age of patients was 53.65+11.84 years. There were 56 (77.78%) males. PMI was detected in 14 (19.44%)patients, with 3-5+- ULN in 13.88% and >5+- ULN in 5.55% of patients. Statistics of study showed that revascularization of left mainstem lesion (1.38 % vs 0 %, p=0.04), in-stent restenosis (2.77 % vs 1.38 %,p=0.03) and procedural complications such as side branch occlusion(1.38% vs 0%, p=0.04) and slow/no reflow (4.16 % vs 1.38 %, p=0.004) were significantly associated with CKMB elevation following complex coronary intervention. Conclusion: PMI is common in patients undergoing complex coronary interventions.

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