Muhammad Usman Siddique, Wajeeha Imran Andrabi, Zeeshan Ahmad, Muhammad Kaleem, Muhammad Ali, Sidra Shoaib Qureshi, Gul-e Lala, Na Qadir, Shaukat Rabbani, Syed Imran Hussain Andrabi, Hasnat Ahmad Butt, Abdul Majeed Chaudhry.
Effect of Use of Ropivacaine as Preemptive Local Anesthesia in Laparoscopic Cholecystectomy.
Pak J Med Health Sci Jan ;13(2):234-6.

Background: Postoperative pain of laparoscopic cholecystectomy is a dilemma. Ropivacaine is reported to have significant control over pain after laparoscopic cholecystectomy. Aim: To get local evidence as if ropivacaine found to be effective in reducing postoperative pain and less analgesia consumption, then in future we can implement the use of ropivacaine as preemptive local anesthesia Methods: This randomized controlled trial was done at Ghurki Teaching Trust hospital, Lahore for 6 months. Sample size of 60 patients was included through consecutive sampling. Then patients were randomly divided in two groups. In group R, 30 patients will be given Ropivacaine. In group NS, normal sa line was given. After surgery patients were shifted to post-surgical wards and were followed-up there for 24 hours. During 24 hours, pain score and analgesia consumption was noted. Data was analyzed in SPSS 21. Results: In group R, the mean age of patient was 41.33+/-10.58 years and in group NS, the mean age of patient was 39.99+/-12.04 years. In group R, there were 19 (63.3%) males and 11 (36.7%) females. In group NS, there were 21 (70%) males and 9 (30%) females. After 24 hours, the mean pain score was 4.73+/-1 .08 in R gro up while 5.47+/-1.17 in NS group (p<0.01) and mean analgesia consumption was 4.00+/-0.91mg in R group while 5.90+/-0.76mg in NS group. The difference was highly significant on (p<0.01).Conclusion: Ropivacaine as preemptive local anesthesia in laparoscopic cholecystectomy is effective in reducing pain and analgesia consumption.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com