Attiqa Khalid, Shagufta Khaliq, Zaima Ali, Maria Gill, Shaheena Naz, Hamid Javaid Qureshi.
Serum Progesterone an Indicator of Viable Pregnancy in First Trimester.
Pak J Med Health Sci Jan ;13(2):219-21.

Aim: To investigate the role of serum progesterone as indicator of viable pregnancy . Methodology : Study was conducted on pregnant women of 8 to 13 weeks of gestation presenting in obstetric department. Status of pregnancy was confirmed on ultrasonography. 53 women having abortion were included in group I, while 28 women with healthy ongoing pregnancy were included in group II. Serum progesterone levels were estimated by ELISA. Median serum progesterone levels were compared between the two groups and receiver operative characteristics (ROC) curve was plotted to find out optimum cut off value of progesterone to assess the viability of a pregnancy . Results: Median serum progesterone levels of abortion group 3.00 ng/ml (1.71 -4.73) were significantly lower than women with viable pregnancy 11.64ng/ml (8.33 -18.44). Serum progesterone level of 6.7 ng/ml is 100% sensitive and 85% specific for viable pregnancy Conclusion: Serum progesterone level can be used to identify viable pregnancy.

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