Vaqar Ilahi Paracha, Anas Ahmad, Imtiaz Ahmed Chaudhry, Mehwish Naseer.
Impact of Aortic Cross Clamp Time on Postoperative Inotropic Support in CABG Surgery.
Pak J Med Health Sci Jan ;13(2):395-8.

Aim: To determine the effect of Aortic clamp time on postoperative inotropic sup port in CABG surgery. Study design: Comparative cross-sectional study. Place and duration of study: Cardiac Surgical Deptt Army Cardiac Centre Lahore from Sep, 2017 to Aug , 2018. Methods: Data was analyzed on 100 patients who had undergone CABG surgery. Group A ( n: 50) included cases with cross-clamp time more than 60 minutes and Group B (n: 50) with cross-clamp time less than 60 min. The primary outcome measure was to estimate requirement of inotropic support in postoperative period. Results: XCL, CPB and operation time was less in Group B and was statistically significant (p 0.000). Prolonged aortic clamp time was not found to be associated with high inotropic support requirement (p 0.175). One patient with preserved LV function in Group A and 8 cases with moderate EF in Group B had requirement of intraortic balloon pump ( p 0.002). Hospital stay was significantly lower in patients of Group A ( p 0.04). In hospital mortality was 2% in Group A and 4% in Group B and was associated with perioperative myocardial infarction ( p 0.55). Conclusion: Prolonged aortic cross clamp time per se does not affect the increase requirement of postoperative inotropic support. Meticulous surgical technique, adequate myocardial protection and avoiding distension insult to heart on weaning off from CPB might play essential role in reducing the need for postoperative chemical and mechanical support.

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