Amina Abid, Ayenah Ali, Qurat-ul ain Mati.
The Association of Erythrocytosis with Uterine Leiomyoma - a tertiary care study.
Pak J Med Health Sci Jan ;13(2):405-7.

Aim: To study the association of Leiomyoma with size, hemoglobin and red blood cell count. Design : Descriptive cross-sectional study. Place and duration of study: Pathology and Gynecology department, King Edward Medical Univers ity (KEMU), Lahore, from December 2018 – May 2019. Methods: Both pre- and post-menopausal females of diagnosed cases of Leiomyoma undergoing myomectomy or hysterectomy were recruited in this study after taking informed consent. Data was collected by 2 students. Patients were interviewed using a proforma containing questions on age, marital status, parity/gravidity, presenting complaints, disease character , type of surgical procedure either leiomyomectomy or hysterectomy, complete blood count and biopsy reports. Written consent was obtained from each participant before their involvement in the study. Data was analyzed by SPSS 23. Quantitative variables, like age and size of Leiomyoma were presented as mean +/- SD. Qualitative variables like marital status, menstrual status either pre-menopausal or post-menopausal and Polycythemia were presented as frequency and percentages. Results : In this study, women who had undergone hysterectomy or myomectomy were between the ages of 20- 60 years. 94% of the women were pre-menopausal and 6% were post-menopausal. 86% were married and 14% were unmarried. Those with parity 0 were 20%, parity 1 (12%) , 2(26%), 3(14%), 4(10%), 5(12%), 6(6%). The most common presenting complaint was pain with abnormal uterine bleeding i.e. 40%, 24% presented with pain only and 36% presented with abnormal uterine bleeding only. Leiomyoma between the sizes of 1-5 cm were 14%, 5-10 cm (38%), 10-15 cm (30%) and >15 cm (18%). 60% of the patients had only one Leiomyoma, 12% had 2 and 28% had >2 Leiomyomas. None of the patients suffering from Leiomyoma had increased Hemoglob in. Most of the patients (68%) had normal RBC count i.e., 3.92-5.13 trillion cells/L , 6% had <3.92 and 26% had RBC count 5.13 trillion cells/L. 36% patients had Hematocrit <34% and 64% had normal values of Hematocrit i.e. 34-54%.Conclusion : Leiomyoma may cause Polycythemia as evident by many researches but our study did not provide decisive affirmation of this association showing no significant correlation between Uterine Leiomyoma with Polycythemia in our set-up.

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