Umar Farooq Qureshi, Muhammad Naveed Aslam, Muhammad Nadeem Ansari, Mohsin Khan.
Renal Manifestation in Kaala Pathar (Paraphenylene Diamine) Poisoning.
Pak J Med Health Sci Jan ;13(2):628-30.

Background: Black stone or chemically known as Paraphenylenediamine is one of the major facilitators of suicide in women particularly. In the last year, 70 women in Punjab alone gave up their lives using black stone over financial troubles, domestic disputes and societal pressure. Black stone that is commonly used in hair dyes and henna is a strong coloring agent. Unfortunately, in the wake of the recently increased number of suicides black stone, commonly known as Kalaa Pathar, is regarded as the cheapest poison for suicide. But,what’s even more concerning is that anyone can get this for only 10 rupees and is still being shamelessly sold in the market. Reportedly, three people are committing suicide every single day in the province of Punjab. The majority of the consumers are women belonging to lower or middle class. Aim: To find out the renal manifestation (acute renal failure) of Kaala Pathar (Paraphenylene Diamine) Poisoning Methodology: This descriptive , cross sectional study was conducted in the medical department of Ibnae–Sienna Hospital Multan from January 2018 to August 2018. Sixty patients were included in the study that ingested kala pathar ( PPD ) by chance and to attempt suicide . The renal manifestation (acute renal failure) of kala pathar (PPD) was recorded on a specific proforma. All data was collected and analysed by using SPSS version 19 Software. Results: Sixty patties were included in the study that ingested kala pathar ( PPD ) accidently and to attempt suicide. Majority of patients have age between 15-20 years, ranging from 10-35 years of age. 40 patients (66 %) out of 60 were female and 20 patients (34%) out of 60 were found male. The renal manifestation of kaal pathar (PPD) was observed as acute renal failure in 58 (97%) patients Two patients ( 3%) out of 60 patients died due to shock, asphyxia and laryngeal spasm. 58 patients (97 %) out of 60 went in to acute renal failure. 55 patients (95%) out of 58 patients having acute renal failure were completely recovered from acute renal failure after prompt medical intervention and 3 (5%) out of 58 patients were having residual renal damage (Serum creatinine 2-4 mg/dl. Conclusion: Significant Renal manifestation (acute renal failure) takes place in kala pathar (Paraphenylene Diamine ) poisoning that can be prevented by using prompt medical intervention.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com