Rukhshan Khurshid, Irsa Asif, Uzma Jabbar, Asad Mahmood Khan, Mumtaz Begum.
Frequency of dyslipidemia in non-obese adolescence and its association with history of diabetes..
Pak J Med Health Sci Jan ;12(1):27-30.

Diabetes is an interaction of environment and genes. Positive family history of diabetes or any other disease in children point out that genetic factors are more important compared to environmental factor. However, environmental risk factors are also prominent with quality of diet and lack of physical activity in the past decades. Methods: This study was included medical student with age range 20-21 years. Student who have positive family history of diabetes were included in the study. A family history of diabetes involving first- degree relatives was recorded via the self-reported questionnaire in the interview survey. Level of fasting blood glucose, total cholesterol, triglyceride, high-density lipoprotein (HDL) cholesterol were measured standard kits using an autoanalyzer. Results: Mean age of male and female subjects was 20 years. Life style was inactive in most of the male/female subjects. Most of the students belong to middle socioeconomic status and their diet was mostly junk food. Level of fasting blood sugar, serum cholesterol, serum triglyceride and lipoproteins LDL-chole, VLDL chol was significantly increased in both male and subjects as compared to their controls. However the level of HDL was not significantly decreased in male/female subjects compared to their controls. Conclusion: Estimation of dyslipidemia in adolescence with positive history of diabetes is reliable and applicable as it may serve the predictor of dyslipidemia and increase risk to develop diabetes.

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