Zafar Iqbal Ghumman, Daleep Kumar, Attaullah Khan.
Comparison of Fine Needle Aspiration Cytology (FNAC) with Excisional Biopsy of Breast Lump.
Pak J Med Health Sci Jan ;12(1):60-2.

Background : Ideal method for diagnosis of breast cancer is arguable. FNAC is a type of biopsy in which cells sample or shatter tissue are obtained for cytological examination from a breast lump using a fine needle method. The needle size may differ from 20 G to 24 G which is mounted on a syringe . Aim : To evaluate the diagnostic accuracy of FNAC on the basis of comparison with excisional biopsy. Methods: This comparative study was conducted on 90 selected patients with some superficial breast lump , who attend the surgery OPD at Allama Iqbal Memorial Hospital Sialkot from May 2009 to April 2010. Firstly, all the cases were experienced FNAC and then excisional biopsy of the breast lump. The sample was evaluated through cytological and histopathological examination in pathology Laboratory . Results: On basis of FNAC, breast lump in 72 patients (80%) diagnosed as benign, 6 patients (6.67%) as malignant and remaining 12 patients (13.33%) were inconclusive. On the basis of histopathology , lumps in 79 patients (87.78%) diagnosed as benign and remaining , 11 patients ( 12.22% ) as malignant. The patients were excluded which were inconclusive in FNAC and the comparison was done in 78 patients. Out of 78 cases, 6 cases (7.69%) were found True Positive, 69 cases (88.46%) found True Negative, 01 case (1.28%) False Positive and remaining 2 cases (2.5 7%) had False Negative results. Conclusion: FNAC is a simple, non-invasive and cost effective technique for early diagnosis. FNAC is an easier procedure than the Excisional Biopsy. This never produce scar in the patients. FNAC can help in surgical management of carcinoma of breast by diagnosis at an early stage.

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