Muhammad Faiq, Anam Shafi, Fozia Khalil, Abdullah Ayub, Aysha Saeed.
To find out the Association of Mortality in Acute Heart Failure patients with Raised Serum GGT.
Pak J Med Health Sci Jan ;12(1):121-2.

Aim : To find out the association of in hospital mortality in acute heart failure patients with raised serum Gamma-glutamyl Transferase . Study Design: Prospective Cohort Study. Study Setting: The study was conducted at medical OPD as well as Medical Emergency department, Services hospital, Lahore. Duration Of Study: Study was completed in Six months after approval of synopsis i.e. from 16-12-14 to 15-06-15. Methodology: 122 with raised GGT and 122 with normal GGT cases with acute heart failure presenting to emergency department of Services Hospital were enrolled in the study. Acute heart failure was diagnosed after initial stabilization of patient by echocardiography. Patients were followed for 7 days to determine hospital mortality. Results: 49 patients (20.1%) died during their stay in hospital. Among 49 patients who died in hospital , 15 were having normal GGT and 34 were having raised GGT. Relative risk for in hospital mortality in acute heart failure patients was 2.67. Older age nullified the association between raised GGT and hospital mortality. Conclusion: There is an association between raised Gamma Glutamyl Transferase (GGT) and hospital mortality in patients with acute heart failure.

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