Tanvir Ahmad Bhatti, Syed Muhammad Aftab Hassan Shah, Waseem Ashraf, Haroon Ashraf.
Correlation of Hypretensive Left Ventricular Hypertrophy with Renal End Organ Damage.
Pak J Med Health Sci Jan ;12(1):291-5.

Aim: To find a correlation , of patients of LVH (cardiac end organ damage) with renal end organ damage . Settings : Cardiology Department Mayo Hospital Lahore. Pakistan Duration: 06 months. February 2011 to August 2011. Methods: This descriptive cross sectional study was conducted in the department of cardiology Mayo Hospital Lahore from February 2011 till August 2011. Sixty (60) Hypertensive patients, 38 (63.33%) male and 22 (35.48%) female were enrolled in for study after informed consent , from out- patient of department of cardiology Mayo Hospital Lahore. They were assessed by 2-D Echocardiography for presence of LVH using standard M-mode section for measurement of Left ventricular posterior wall and interventricular septum thickness in left lateral decubitus position. Urinary albumin excretion (microalbuminuria) for 24 hours and urinary creatinine clearance were measured by collecting urine for 24 hours. Both were used as markers for renal insufficiency. Results: The mean age of patients was 50.58+/-10.42 with minimum observed age of 30 years and maximum age of 70 years. There were 38 (63.33%) male and 22(35.48%) female patients included in the study. The microalbuminuria was found to be 52.64+/-72.92 with minimum observed value of 4 and maximum value of 282.00. Out of total 60 patients microalbuminuria was present in 16(26.67%) and was absent in rest of 44 (73.33%) subjects . The mean creatinine clearance observed was 92.69+/-18.35 with minimum observed value of 32.00 and a maximum value of 12 0 ml/min . The level of creatinine clearance was normal in 47(78.33%) patients and it was towards mild renal insufficiency in 12(20%) patients. Moderate renal insufficiency was noted in 1(1.67%) patient. The mean value of LV posterior wall thickness as determined by echocardiography was 1.30+/-0.17 with minimum observed value of 1.20 cm and a maximum value of 1.90cm .

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