Sohail Bashir Sulehria, Naeem Aslam, Adnan Ahmad Athar.
Extra Intestinal Manifestations of 100 cases of Ulcerative Colitis and its correlation withextent and behavior of disease.
Pak J Med Health Sci Jan ;12(1):296-8.

Aim : To identify frequency of extra intestinal manifestations, correlate them with the extent of involvement of colon and severity of disease and determine the effect of presence of extra intestinal manifestation on relapsing / remitting pattern of disease in patients of ulcerative colitis. Study Design : Case control type of cohort study carried out in Mayo Hospital, Lahore. Results: Colonoscopic extent shows that there were 27% patients who had proctitis, 22% had distal colitis, 13% had left sided colitis, 17% had extensive colitis, 15% had pancolitis and 6% had pancolitis with backwash ileitis. Colonoscopic severity shows that 26% had grade II, 21% had grade III and 53% had grade IV.EIM were observed in 6%, out of which only 1 (16%) had proctitis while 3 (50%) had pancolitis and 2 (34 %) had pancolitis with backwash ileitis. Extra intestinal manifestations were significantly higher in patients with pancolitis and pancolitis with backwash ileitis. . Conclusion: Frequency of EIM in our study was 6% and its presence is significantly associated with extent of disease but has no significant association with behavior of disease.

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