Asifa Ashraf, Saqib Sohail, Tahira Saleem.
Assessment of Glutamate Levels in Neonates Suffering from Hypoxic Ischemic Encephalopathy.
Pak J Med Health Sci Jan ;12(1):327-9.

Aim : To assess the glutamate level in neonates suffering from Hypoxic Ischemic Encephalopathy. Study design : Descriptive analytic study Place and duration of study: This study was conducted at the University of Health Sciences (UHS) Lahore in collaboration with Services Hospital Lahore. Methodology : Eighty-four neonates admitted in neonatal Unit of tertiary care hospital had been included. Neonates were classified as hypoxic on the basis of Sarnat and Sarnat scoring. 34 healthy neonates served as control. Among 50 patients two groups were made each containing 25 neonates. Group 1 comprising of 25 neonates suffering from hypoxic ischemic encephalopathy of mild degree. Group 2 comprising of 25 neonates suffering from moderate to severe encephalopathy. Results : The level of serum glutamate was significantly higher in neonates suffering from hypoxic ischemic encephalopathy . Conclusion : Elevated levels of serum glutamate summarizes the role of glutamate in neonates suffering from hypoxic ischemic encephalopathy .

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