Muhammad Anwar, Samra Ismat, Jawad Hussain Qamber, Mussarat Bano.
Bronchopulmonary Dysplasia: a Hazard Factor in Preterms due to Maternal / Neonatal Vitamin D Inadequacy.
Pak J Med Health Sci Jan ;12(3):1291-5.

Aim: To explore the conceivable relationship between maternal/neonatal 25-hydroxy vitamin-D (25-OHD) levels and advancement of bronchopulmonary dysplasia (BPD) . Methods: This prospective study was conducted at Ch. Rehmat Ali Trust Hospital Lahore from 1st July 2017 to 31st December 2017. Two hundred preterms newborn children less than or equal to 32-weeks of gestation, who were determined to have respiratory trouble disorder were enlisted. 25-hydroxy vitamin-D levels were resolved in maternal/neonatal blood tests that were acquited at the time of admission to neonatal emergency unit. Congenital and chromosomal anomalies and infants who died before 36-weeks of gestation were not included in the study. Results: Bronchopulmonary dysplasia was developed in 62 (31%). In bronchopulmonary dysplasia group, both maternal and neonatal 25-hydroxy vitamin D levels were essentially lower contrasted with those in no bronchopulmonary dysplasia group ( P< 0.0001). A positive relationship was identified amongst maternal andneonatal 25-hydroxy vitamin-D levels. All of bronchopulmonary dysplasia infants had 25-hydroxy vitamin-D level <10ng ml-1, which shows sever inadequacy. Univariate logistic regression investigation uncovered that maternal/neonatal vitamin-D levels were critical indicator of bronchopulmonary dysplasia. Odd ratio was 0.76 and 0.61 respectively, p<0.001.Conclusion: We exhibited out of the blue that lower maternal and neonatal vitamin 25-hydroxy vitamin-D levels were related with bronchopulmonary dysplasia advancement in preterm babies. However, additionally thinks about bigger example sizes are expected to depict the conceivable connection between vitamin-D deficiency and bronchopulmonary dysplasia.

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