Aalia Hameed, Mateen Izhar, Shazia Hameed, Muhammad Fayzan.
Neonatal Sepsis in Tertiary Care Hospital: Bacteriological Profile and Antibiotic Susceptibility Patterns.
Pak J Med Health Sci Jan ;12(4):1656-8.

Aim: To determine the most common pathogen responsible for neonatal sepsis and their antimicrobial sensitivity Method : This retrospective cross-sectional study was carried out in the Department of Microbiology, Shaikh Zayed Hospital, Lahore from March 2017 to April 2018. A total of 618 samples were received with history of neonatal sepsis. All samples of blood culture were received from neonatal ward with history of sepsis. All patients were between the age of 1-28 days. Blood culture results and their antibiotic sensitivity were collected and analyzed. Results: Blood cultures were positive in 85 (13.75%) cases. The isolated pathogens in early and late onset sepsis were 60% and 40% respectively. The blood cultures reported the most prevalent isolate in early and late onset neo- natal sepsis was the coagulase negative Staphlycoccus (CONS) 44.7%, followed by Klebsiella 16.47%, Staphylococcus aureus 8.23%, Citrobacter/Eneterobacter 9.41%, and Acinetobacter 7.05%, Escherichai coli and Pseudomonas were 5.88%. Conclusion: Coagulase negative Staphylococcus is a major cause of neonatal sepsis.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com