Maria Ashfaq, Saima Rafique, Romana Latif, Tahira Yasmeen, Sara Gulbaz, Zahida Kalsoom, Saima Javeed.
Pipelle Endometrial Biopsy- a Safe Alternative to Dilatation and Curettage in Selected patients.
Pak J Med Health Sci Jan ;13(1):99-101.

Background: Abnormal uterine bleeding in perimenopausal and postmenopausal women is associated with endometrial carcinoma in approximately 10%. Endometrial biopsy is mandatory in these patients. Endometrial sampling with Pipelle is outdoor, cost effective and a safe procedure Aim: To assess efficacy of Pipelle sampling in selected high risk patients. Methodology: A descriptive study was carried out in Nawaz Sharif Social Security Teaching Hospital Multan road, Lahore from May 2017 to November 2017.Total no. of 33 patients were included in this study, who presented with abnormal uterine bleeding, have co morbidity and evidence of thickened endometrium on Ultrasonography. Pipelle sampling was used as diagnostic tool to obtain endometrial biopsy after informed consent. Histopathology reports were followed and reports showing malignancy were confirmed by specimen obtained on laparotomy. Results: The most common age group was 46-55 years that is 24(72.7%). 45% patients had parity >4. Most common presentation was irregular vaginal bleeding (78%). Ultrasound (USG) findings showed increased endometrial thickness in 16(48%) perimenopausal age group and 4(12%) in postmenopausal age groups. Histopathology reports showed hormonal imbalance in 21(63%), endometrial hyperplasia in 2(6%), endometrial carcinoma in 4(12%), chronic endometritis in 2(6%). Conclusion Pipelle sampling is an effective tool to diagnose endometrial pathology in patient with thickened endometrium and co morbid conditions where general anesthesia can be avoided by choosing pipelle.

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