Syed M Raza, Aamir M Ijaz, Rashid A Malik, Abdul Mateen.
Incidence of Reactivation of Tuberculosis in cases of Aspergilloma Secondary to Previously treated Cavitary Tuberculosis.
Pak J Med Health Sci Jan ;13(1):105-6.

Background: Aspergilloma is a condition in which a fungus ball is formed within a pre-existing intrapulmonary cavity. Cavitary tuberculosis is the most common cause of aspergilloma in our settings. Aim: To observe the incidence of reactivation of tuberculosis in cases of Aspegilloma secondary to previously treated Cavitary Tuberculosis. Methodology: This descriptive prospective interventional study was conducted at the department of Thoracic Surgery, King Edward Medical University/Mayo Hospital, Lahore between December 2015 and May 2018. Results: 58 patients, 38 males and 20 females, with aspergilloma after a previously treated cavitary tuberculosis were subjected to flexible bronchoscopy to obtain Bronchoalveolar lavage which was sent for detection of MTB using GeneXpert method, as well as for detection of fungal spores. None of the samples tested positive for MTB in the presence of aspergilloma. Conclusion: Based on our results, we concluded that reactivation of tuberculosis was not seen in patients with aspergilloma after a previously treated cavitary tuberculosis.

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