Shahzad Ali Jiskani, Rizwan Ali Talpur, Kumayl Abbas Meghji, Qandeel Soomro.
Seropositivity of hepatitis B and C among volunteer blood donors at Tando Muhammad Khan.
Pak J Pathol Jan ;30(3):69-71.

Objective:To determine seropositivity of hepatitis B and C among voluntary blood donors. Material and Methods:It was a prospective study, performed in Blood Bank Indus Medical College Hospital Tando Muhammad Khan for a period of 2 years (January 2017 to December 2018). Patients between 18 and 50 years, no history of hepatitis or any other comorbid conditions and weight more than 50 kg were included in the study. Both first time and repeat donors were also included. All donors were screened for hepatitis B, C and HIV with automated enzyme immunoassay analyzer MINDRAY C1000i. Results:A total 3028 blood donors were included in the study. Out of 3028 donors, most were males i.e.3020 (99.7%) and only 8 (0.3%) were females. Among 3028 blood donors, 41 (1.38) were found to be positive for hepatitis B (HBsAg) and 65 (2.14 %) were positive for anti HCV. Conclusion:Hepatitis C infection was found to be more commonly transmissible than hepatitis B infection. Blood donation is the major cause of transmission of life-threatening diseases e.g. Hepatitis B and C. The transmission of these infections can be prevented by employing proper donor screening using various serological diagnostic methods of high sensitivity and specificity.

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