Fareeha Shahid, Farhan Muhammad Qureshi.
Pre-Pregnancy Obesity: a friend or foe for Vitamin D.
J Bahria Uni Med Dental Coll Jan ;10(1):84-5.
Vitamin D and its active metabolite 1,25 - dihydrooxyvitamin D (1,25(OH) 2D) has been generally recognized as repertoire of many classical (calcium balance and bone metabolism) and non-classical effects (non-calcium actions) such as promotion of insulin secretion and its action, immunomodulation. Absorption of calcium and phosphorus depends on sufficient vitamin D levels. Its low level leads to demineralization of bone both in children and adults. Vitamin D has also a significant role and has potential to influence many factors in the developing fetus. Newborns are at high risk of developing hypocalcaemic tetany as a consequence of maternal deficiency of vitamin D.
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