Salva Shah, Mohtasim Billah, Nazish Shinwari, Adeel Basharat, Maheen Shah.
Study of Hematological Parameters in Plasmodium Vivax Malaria in Mardan, Khyber Pakhtunkhwa.
J Saidu Med Col Jan ;9(2):265-9.

Background: Malaria is among the most prevalent infections of the world. It is caused by plasmodium species which are parasites of blood thus inducing hematological alterations. Objective: This study was done to observe the complete hematological profile in Plasmodium vivax induced malaria patients and the associated microscopic findings in these patients. Materials & Methods: This was a cross-sectional study done in Mardan Medical Complex, Mardan during July to November, 2018. 100 cases of Plasmodium vivax malaria whose diagnosis were confirmed through Giemsa stained thick and thin blood films were taken through consecutive sampling. Hemoglobin (Hb), hematocrit (HCT), mean corpuscular volume (MCV) , mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), red cell count (RCC), total leucocyte count (TLC) and platelet count were done using hematology analyzer and detailed microscopy was done to find other morphological changes in red cells. Results: Age range of patients was 4 to 66 years. 60% of positive cases were males and 40 % females. Thrombocytopenia was the most common hematological abnormality present in 70% patients followed by anemia which was seen in 58% of patients. Microcytic hypochromic was the commonest blood picture in anemic patients. Leucopenia was present in 3% of patients only while leukocytosis in 15% of patients. Conclusion: Thrombocytopenia and anemia were the most common associated abnormalities in P. vivax malaria whereas microcytosis and hypochromia were the most common microscopic findings.

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