Shazia Ijaz, Haris Bin Bilal, Junaid Sultan, Tariq, Badar Bin Bilal, Waqar Ahmed, Ashraf M, MBY Bilal.
Comparison & efficacy of different Cardioprotective techniques during CABG assessed by metabolic & chemical markers.
Pak J Cardiol Jan ;14(2):49-58.

It was a prospective and randomized study of 124 consecutive patients scheduled for elective surgery at AFIC/NIHD. Patients were assigned to cold crystalloid cardioplegia, warm blood cardioplegia & cold blood cardioplegia groups. Patients were comparable with respect to preoperative data and cardiac status. Biochemical measurements, metabolic indices & post operative morbidity and mortality were evaluated before and after the operation. CPK, CK-MB, AST, LDH & ALT measurements were significant among different groups. Their concentrations were highest after cold crystalloid cardioplegia and least after warm blood cardioplegia. The warm blood cardioplegia appears to confirm best myocardial protection, cold blood cardioplegia lies in the center and cold crystalloid ardioplegia exerts sub-optimal degree of myocardial protection. This study provides guidelines for the selection of a better cardioplegia solution giving optimal results.

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