Bushra Bano Patoli, Atif Ahmed Patoli, Sualeheen Shaikh, Shankarlal Rathi.
Gastric biopsy examination for h. pylori associated gastritis and host related risk factors in the indigenous population at hyderabad, pakistan.
Rawal Med J Jan ;44(1):11-5.

Objective: To investigate the burden of Helicobacter pylori (H. pylori) associated gastritis and its association with various host factors in the indigenous population. Methodology: Histopathology was performed in 200 samples from patients with dyspepsia. Results: Of 200 samples, H. pylori was detected in 127(63.5%) cases associated with gastritis. Percentages of positive cases for males and females were 64.5% (n=62) and 62.5% (n=65), respectively. The analysis suggested an impartial impact of gender on H. pylori infection [OR=1.09, CI=(0.61–1.95), p=0.771]. Significantly strong positive correlation between age and H. pylori associated gastritis was seen [r =0.938, p-value =0.0005]. However, relatively weaker correlation was observed for female than male category [Female; r =0.353 and Male; r =0.908]. H. pylori infection was only observed in patients with Rh-positive blood group phenotype and high frequency gastritis was observed in case of O-positive blood group. Conclusion: H. pylori associated gastritis was observed independent of gender whereas the frequency of H. pylori infection was observed more frequent with the increasing age of patients. The detection of H. pylori was highly prevalent in gastritis patients having O-positive blood group in Hyderabad, Pakistan.

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