Iftikhar, Qazi Abdul Saboor, Amir Khan, Amber Malik, Qazi Muhammad Tufail, Husnain Bashir, Abubakar Hilal, Mohammad Abdul Rehmaan.
The Effect of Percutaneous Coronary Intervention on the Ejection Fraction of Left Ventricle.
J Cardiovascular Dis Jan ;15(3):68-72.

BACKGROUND & OBJECTIVE: To see the effect of percutaneous coronary intervention (PCI) on ejection fraction (EF) of left ventricule in patients of ST segment elevation myocardial infarction. MATERIAL & METHODS: This Quasi experimental study done at Cardiology department of Sheikh Zayed Hospital, Lahore during the period of one year from October 2015 to October 2016. 56 ST elevation myocardial infarction (STEMI) patients were included in the study who underwent PCI. There pulse and blood pressure were recorded. The information regarding myocardial infarction and peripheral vascular disease was noted. 2D Simpson`s bi-plane method was used on echocardiography to determine the left ventricular ejection fraction (LVEF) before the interventional procedure and then after PCI during hospital stay. The comparison of LVEF before and after PCI was compared by using paired sample t-test. Significant p value was considered as <=0.05. RESULTS: Before PCI, 47.61 +- 4.32 was mean LVEF while after PCI, 51.61 +- 4.31 was mean LVEF. Paired t-test was used and it was inferred that there is appreciable mean difference between LVEF before and after intervention (p<0.000006). CONCLUSION: This study demonstrated that LVEF improves after PCI in STEMI patients with reduced LVEF. Thus PCI should be offered to every patient of STEMI with reduced LVEF.

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