Hasina Sadiq, Irum Sohail, Maria Habib.
Analgesic Efficacy of Ropivacaine versus Lignocaine in Perineal Tears: a Randomized Controlled Trial.
J Islamic Int Med Coll Jan ;14(4):179-83.

Objective: To compare the analgesic efficacy of Ropivacaine (0.75%) with Lignocaine (2%) in reducing the pain of perineal tears during suturing and postpartum. Study Design:Randomized Controlled Trial. Place and Duration of Study: This prospective trial was conducted in Gynecology and Obstetrics department of Kahuta Research Laboratories (KRL) hospital, Islamabad over the period of 3 months from May 2018 to August 2018. Materials and Methods: In this study 100 patients with singleton pregnancy and vertex presentation undergoing vaginal deliveries were randomly divided into either 2% Lignocaine group or 0.75% Ropivacaine group on the basis of subcutaneous infiltration of the corresponding local anesthetic before perineal repair. Main outcomes studied between the 2 groups include mean pain scores assessed by Visual analogue scoring system (VAS) at the time of suturing and then at 30 mins, 3 hours and 6 hours post partum. The need for additional local anesthetic, on-demand analgesia and side effects were also noted. The outcomes between the two groups were compared and analyzed by SPSS version 23. Results: A total of 100 women were randomized and equally allocated into one of the two groups. Mean pain score of Ropivacaine was compared with lignocaine and was found to be significantly reduced at the time of suturing (p=0.005), 3 hours (p=0.00) and 6 hours (p=0.001) post partum. But no statistical difference was found in pain score at 30 minutes post partum (p=0.713). The need for additional local anesthetic at suturing (p=0.004) and need for on-demand analgesia (p=0.001) was higher in Lignocaine group. No side effects were noted in both groups. Conclusion: Ropivacaine was more effective in reducing post episiotomy perineal pain as compared to lignocaine.

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