Rubina Zulfqar, Tariq Mehmood, Komal Rehman.
Cord Blood Albumin as a Predictor of Significant Hyperbilirubinemia in Term Neonates.
J Islamic Int Med Coll Jan ;15(1):37-40.

Objective: To determine the frequency of jaundice at a cut off level of <2.8 gm/dL of the cord blood albumin in full term babies. Study Design: Descriptive case series study. Place and Duration of Study: This Research was done in Pediatric Department, Holy Family Hospital, th th Rawalpindi from 27 July 2013 to 27 January 2014. Materials and Methods: Seventy term neonates, delivered by any mode of delivery and normal birth weights were included. Cord blood albumin level was sent. Neonates were divided into two groups. Group I was having cord blood albumin levels equal to or less than 2.8gm/dl and group II had level above 2.8gm/dl. They were followed in OPD at 72 hrs of life for development of jaundice. Jaundice was assessed clinically by Kramer dermal zones method and confirmed by serum total bilirubin level estimation. All information was recorded in predesigned proforma. Data was analyzed by using SPSS Version 23. Chi square was used to calculate frequency of jaundice in two groups of neonates. Results: Mean cord blood albumin level was 3.23+-0.86 gm/dL. Frequency of jaundice was significantly high in group I-71.9% versus 15.8% in group II (p=0.0005). Stratification analysis was performed with respect to gender for frequency of jaundice. It was again significantly high in group I compared to group II, irrespective of sex. (p=.001 and.002 respectively). Conclusion: It is concluded that full term babies having cord blood albumin level <2.8 gm/dL are at risk to develop neonatal jaundice.

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