Muhammad Asif Gurmani, Muhammad Khalid, Muhammad Faizan.
Comparison of Increase in Intra-Vaginal Ejaculatory Latency Time (IELT) with Fluoxetine and Placebo in patients of Premature Ejaculation.
J Uni Med Dent Coll Jan ;10(1):30-6.

OBJECTIVES:Compare the mean increase in Intra-vaginal ejaculation latency time (IELT) with the fluoxetine and placebo in patients of premature ejaculation.STUDY DESIGN:Randomized Control TrialPLACE AND DURATION OF STUDY:Study was conducted at Department of urology, Teaching Hospital Dera Ghazi Khan, from 5th Jan 2017 to 4th Jan 2018 for period of one year. METHODOLOGY:Eighty patients were included to compare the mean increase in intravaginal ejaculatory latency time (IELT) with fluoxetine and placebo in patients of premature ejaculation. The data was collected by a specially designed performa and the analyzed through SPSS-13. RESULTS:Majority of the patients in both groups were found between 41-51 years of age, in Group-A 35%(n=14) and 30%(n=13) in Group-B. Mean and standard deviation was recorded as 37.49+-6.536 in Group-A and 35.69+- 5.493 in Group-B. The pre-intervention intravaginal ejaculatory latency time (in seconds) was recorded in Group-A 48.17+-2.66 while 48.75+-2.78 in Group-B, which was found insignificant, while on post-intervention was found 176.20+-6.61 in Group A while 65.22+-2.64 in Group-B, p-value was 0.00, and we further recorded mean increase in intravaginal ejaculatory latency time (in seconds) also which shows mean 128.02+-6.51 in Group-A and only 16.47+-3.86 in Group-B and it was found highly significant, p value was found 0.00 which is <0.05.CONCLUSION:Fluoxetine is an effective drug for the treatment of premature ejaculation.

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