Syed Waseem Ahmad Mujtaba, Awais Anwar, Abdul Matin Qaisar.
Examine the Incidence of Liver Cancer in patients Presented with Hepatitis B Virus and Hepatitis C Virus Infection.
Med Forum Jan ;31(2):59-62.
Objective: To examine the prevalence of hepatocellular carcinoma in hepatitis B virus and hepatitis C virus patients. Study Design: Prospective study. Place & Duration of Study: This study was conducted at the Department of Medicine, Amna Inayat Medical College, Sheikhupura from July 2017 to December 2019. Materials and Methods: One hundred and twenty patients of both genders clinically diagnosed to have Hepatitis B and Hepatitis C virus were included in this study. Patient`s demographical details were recorded. All patients were newly diagnosed and free of hepatocellular carcinoma. All the patients were underwent abdominal ultrasound, computerized tomography scan and AFP at every 6 months for diagnosing hepatocellular carcinoma. Mortality was recorded. Final follow-up was taken at 2 years. Results: There were 75 (62.5%) male patients while 45 (37.5%) female patients. 25 (20.83%) patients were ages 25 to 40 years, 52 (43.33%) patients were ages 41 to 55 years, 30 (25%) had ages 56 to 70 years and 18 (15%) were above 70 years. 56 (46.67%) patients had Hepatitis B virus and 42 (35%) had hepatitis C virus and 22 (18.33%) had co-infection of hepatitis B virus and hepatitis C virus. Hepatocellular carcinoma was diagnosed in 8 (6.67%) cases at final follow-up. 4 (3.33%) patients were died during the study period. Conclusion: Prevalence of hepatocellular carcinoma in our study was high. Hepatitis B virus and hepatitis C virus and co-infection considered a major cause for developing hepatocellular carcinoma.
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