Abdur Rasheed Khokhar, Khowaja Faiz Ur Rab, Hafiz Usman Akhtar.
Outcome of Macular Hole Surgery.
J Coll Physicians Surg Pak Jan ;13(10):569-72.

Objective: To document the outcome of macular hole surgery in terms of improvement of visual acuity and the duration of closure of macular hole. Design: Interventional quasi experimental study. Place and Duration of Study: Ophthalmology Department, Civil Hospital, Karachi. Subjects and Methods: Twenty-four eyes of 22 patients with macular hole underwent surgical repair. Vitrectomy with maculorrhexis (internal limiting membrane peeling) and fluid-gas exchange followed by prone positioning for one to two weeks was carried out. Postoperative follow-up was done for one year. Main outcome measures were visual acuity, closure of macular hole and ocular complications. Data was analyzed by using SPSS Version 10. Non-parametric sign test with chi-square statistic was used to compare the pre-operative and postoperative outcome. Results: The macular hole was successfully closed in 17 eyes that revealed high statistical significance regarding improvement in visual acuity. Earlier, significant improvement figured in 17 / 24 cases was observed at three-month post- operative examination (p < 0.0001). An insignificant success figured in 8 / 24 due to postoperative complications at six-month follow-up. Visual acuity improved upto two or more lines in 17 eyes at one-year follow-up. Twelve cases developed cataract, 7 developed increased intra-ocular pressure (transient), one had glaucoma and one retinal detachment. Conclusion: Vitrectomy with maculorrhexis (internal limiting membrane peeling) and fluid-gas exchange can successfully close macular holes and improve vision.

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