Anjum R, Siraj Mr, Tahir Tm, Javed M, Farrukh K, Masood M, Naseem N.
Keratinizing Pleomorphic Adenoma in Minor Salivary Gland: a Case Report.
Biomedica Jan ;35(4):191-3.

Pleomorphic adenoma (PA) is the most common benign mixed tumor of the salivary glands characterized by broad variation in the stromal and parenchymal differentiation by tumor cells. 1 This neoplasm makes up to 73% of all salivary gland tumors. Parotid gland is the most commonly involved site. Globally, 14.0% to 52.0% of salivary gland tumors affect minor salivary glands and out of them up to 67.0% are benign. 2 PA affects females (60%) more frequently than men and (40%) present in the fourth, fifth, and sixth decades of life. 3 Clinically, it presents as an asymptomatic, slow growing swelling. 4 The optimal treatment for pleomorphic adenoma is comprehensive excision with safety margins and regular follow up for at least 3-4 years because of the high risk of recurrence.

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