Amber Kiyani, Anam Zahid Kiani, Uzair Luqman 204 20.
Secondary Amyloidosis Presenting as Oral Nodules.
J Pak Dent Assoc Jan ;28(4):204-6.

Secondary amyloidosis is a consequence of chronic inflammatory diseases that results in deposition of amyloid in organs disrupting its function. Oral involvement with this process is exceedingly rare. A 63-year-old Pakistani female with a history of rheumatoid arthritis and ankylosing spondylitis was seen in the Oral Medicine Clinics for painful oral nodules that were diagnosed as AA-type, or secondary amyloidosis, following an incisional biopsy. Similar deposits were identified in vital organs on subsequent examination by the patient`s physicians. Due to widespread systemic involvement, our patient died within 6-months of her diagnosis. CONCLUSION: This case serves as a reminder that oral presentations may be the first identifiable signs of systemic diseases. It also emphasizes the importance of multidisciplinary clinical practice, and the lack of it in our country.

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