Muddassir Ahmed, Fazl-e Mateen, Ahmed Ayyaz, Maria Muddassir, Ahmad Basirat, Sajad Ahmed.
Association of vitamin D deficiency with microalbuminuria in type II diabetics.
Pak J Med Health Sci Jan ;13(4):925-7.

Aim : To find out whether or not an association exists between Microalbuminuria and deficiency of Vitamin D in our diabetic population. Methods: This cross sectional analytical study was carried out in out-patient department of Nephrology and Diabetes Centre , Sheikh Zayed Hospital, Lahore after approval from Ethical Committee and IRB, over a period of one year. The study included 312 patients, 156 patients had microalbuminuria and 156 patients were normoalbuminuric. Their 25(OH) vitamin D levels were measured by a single specified laboratory. Effect modifiers like age and gender were controlled through stratification. The comparison in Vitamin D levels amongst both groups was done using independent sample t -test. Results: Out of 156 patients who had no microalbuminuria (ACR<30 mg/g of creatinine), 51 patients had vitamin D deficiency (32.6%). However in patients with microalbuminuria (ACR 30 -300mg/g of creatinine), 115 out of 156 patients (73.7%) had vitamin D deficiency. Conclusion: This study states that an association exists between Vitamin D deficiency and microalbuminuria in type 2 diabetes. It is also reported that incidence of Vitamin D deficiency is more as compared to normo - albuminuric patients.

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