Tariq Farooq Babar, Zubair Masud, Nasir Saeed, Irfan Wazir, Muhammad Daud Khan.
A two years audit of admitted patients with the diagnosis of endophthalmitis.
Pak J Med Res Jan ;42(3):105-111.

We carried a retrospective hospital based case study from December 2000 to November 2002. The objectives of our study were to determine the number and different causes of endophthalmitis requiring hospitalization and to study the relative frequency of endophthalmitis following intraocular surgery. Secondly to study the final visual outcome of endophthalmitis and its relationship to its etiological causes. Out of total of 9100 patients admitted during the period of December 2000 and November 2002, 170 (1.86%) patients had endophthalmitis. Most of the patients affected were children below 15 years of age {66 cases (38.82%)} followed by adults over 60 years {51 cases (30%)}. Male were affected more than female {100 cases (58.82%) vs 70 cases (41.17%)}. The most common predisposing factors for endophthalmitis were trauma {90 cases (52.94%) followed by post operative {73 cases (42.94%)} corneal ulcers {4 cases (2.35%)} and endogenous {3 cases (1.76%)}. A total of 7900 intraocular surgeries were performed and 48 cases (0.60%) developed postoperative endophthalmitis following ECCE ± IOL, ICCE ± IOL or phaco ± IOL, peripheral iridectomy and trabeculectomy. In the post-traumatic group, 56.86% presented within 5 days of trauma while 21.11% presented between 5 – 15 days and 22.22% beyond 15 days, while in the post-surgical group 58.90% had delayed presentation. Vitrectomy and systemic antibiotics were required in 54 patients (31.7%). The visual prognosis was found to be poorer in the traumatic group as compared to post surgical group. Only 21.1% patients had regained useful visual acuity in the traumatic group as compared to 27.3% in the post surgical group, while only 16.6% patients had regained moderate visual acuity in the traumatic and 27.3% in the post surgical group. Trauma is the leading cause of endophthalmitis in this part of the world. Post surgical endophthalmitis is the second common cause of endophthalmitis. The visual outcome is poorer in the traumatic group because of severity of infection, the delay in presentation and the associated ocular pathologies. We need to make major efforts in designing and implementing appropriate strategies in the field of prevention of ocular trauma, proper management of trauma and prevention and management of postoperative intraocular infection.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com