Muhammad Bilal Nasir, Junaid Mushtaq, Maria Aslam, Ghias-un Nabi Tayyab, Shafqat Rasool, Ibtessam Amjad, Ghias-ul Hassan, Israr-ul Haq.
Prevalence of hepatitis B & C in end stage renal disease on treatment of chronic / long-term hemodialysis.
Pak J Med Health Sci Jan ;13(4):1027-9.

Background: Hepatitis B & C are worse conditions and are more likely to be common in patients of end stage renal disease taking hemodialysis . The incidence varies in different regions of the world. Aim: To assess the prevalence of Hepatitis B and Hepatitis C viral infection among ESRD patients on chronic long-term hemodialysis at a community hospital. Methods: Cross sectional study was done on 171 ESRD registered cases from 2009-2014. Viral serology was done to confirm presence of Hepatitis B or C virus by rapid immuno-chromatographic test (ICT). Results: There were 103/171 (60.2%) males and 68 (39.8 %) females with mean age of 43.82± 14.44 years. The factor caused ESRD were 58.5% hypertension, 33.2% diabetes and 25% had ischemic heart disease . There were 31.6% who had vaccination for HBV. In this study, 69% were found positive for HBV or HCV . For HBV 54.97% while for HCV 11.11% had positive serology while 0.03 % were positive for both HBV & HCV. Of the 94 HCV positive patients, 25 were vaccinated for HBV. Conclusion: The incidence of Hepatitis B & C viral infection is common in ESRD patients on chronic long-term hemodialysis in poor resource countries, with low vaccination rate of HBV. The seroprevalance for HCV rises abruptly with duration of dialysis.

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