Ahsan Jamil, Rubab Javed, Nighat Nadeem, Kamil Shujaat, Shumaila Shakoor, Aysha Babar, Talha Laique.
Comparison of harmonic scalpel method with conventional procedure for intraoperative blood loss during thyroidectomy among Pakistani patients.
Pak J Med Health Sci Jan ;13(4):1172-4.

Background: Thyroid glands have a complex blood supply, so it becomes necessary to have a proper hemostasis during its surgery. In conventional method, hemostasis is secured by using ties and sutures. Aim: To compare the intra-operative bleeding in Pakistani patients with multinodular goiter undergoing thyroidectomy with harmonic scalpel method versus Conventional hemostasis. Study design: It was prospective randomized controlled trial. Methodology: All patients underwent thyroidectomy for Multinodular goiter were distributed into two assemblies, Group A (Harmonic Scalpel Method) and Group B (Conventional Technique). In Group-A, harmonic scalpel ligated all thyroid vessels. In Group B, inferior middle and superior were tied using silk sutures 3/0 , and all other vessels were sutured by 4/0 or electrocauterized . The two groups were compared for Intra -operative blood loss. Results: The mean blood loss of patients in group A was 70.03 ± 5.70ml and in group-B was 96.43±5.93 ml with p value of 0.00001 which is statistically significant. All the data was entered and processed by analysis made using SPSS v23.0. Conclusion : Harmonic scalpel represents a safe alternative to conventional technique with a significant reduction of blood loss in thyroidectomy.

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