Shaima Sultana Memon, Pushpa Valiram, Saleh Memon.
Clinico-pathological profile of breast lesions at a tertiary care centre in Karachi, Pakistan.
Pak J Surg Jan ;36(1):25-8.

Objective: To conduct a four-year audit of breast pathology at a tertiary care center in Karachi, Pakistan. Material and Methods: This was a retrospective study of all breast pathology specimens received over a four-year period from January 2015 to December 2018 at the Department of Pathology, Dow Medical College, Dow University of Health Sciences (DUHS), Karachi, Pakistan. A total of 257 breast specimens were received during the study period. Th eir reports were retrieved and data was collected, entered and analyzed using SPSS version 24.0. Results: Out of 257 patients, 246 (95.7%) patients were female and 11 (4.3%) were male. Out of 257 breast specimens, 211(82.1%) biopsies were reported as benign and 46 (17.9%) as malignant. The commonest benign lesion was fibroadenoma, comprising 151 (58.75%) cases. Fifteen of these were bilateral. The second common benign lesion was abscess, Th e commonest malignancy was infiltrating ductal carcinoma, comprising 84.8% of all malignancies. Conclusion: Our findings were similar to the findings of other studies done in the Indo-Pak subcontinent. Further studies are required to identify epidemiology of breast disease in Pakistan so that appropriate health services and policies may be planned and executed.

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