Sanaa Ahmed, Maria Naz, Batool Bibi, Hira Tariq, Aisha Naureen, Sadaf Talha.
Frequency of developmental defects of enamel and dentin in patients coming to tertiary care clinic of Karachi.
Pak J Surg Jan ;35(4):320-4.

Objective: The objective of the study was to find out the frequency of enamel and dentine developmental defects in patients presenting in tertiary care facility. Study design: Retrospective descriptive cross-sectional study Setting & Duration: Data of 10,125 patients coming to oral medicine/diagnosis outpatient department of Sindh Institute of Oral Health Sciences from November 2016 to November 2017 was reviewed. Material and Methods: Retrospective analysis of data of 10,125 patients coming to oral medicine, diagnostic out patient department was done. Sampling technique was convenient. Data of 13 patients who were diagnosed on basis of clinical criteria were included. Statistical analysis was done through spss17. Results: Data of 10,125 patients was reviewed, out of which 13 patients diagnosed with developmental disorders of enamel and dentine were included in this study. 10 patients were diagnosed with Amelogenesis imperfecta, fluorosis was found in 2 and 1 case of Dentinogenesis Imperfecta was found. Conclusion: Amelogenesis imperfecta and fluorosis are more common than Dentinogenesis imperfecta in our region in comparison to western countries. A more comprehensive study on the severity of these defects in Pakistani population and relation to the etiology of these defects are required as due to difference in ethnic background and inter-familial marriages, inheritable diseases are relatively more common in our society

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