Syed Shamsuddin, Erum Najeeb, Tassawar Hussain Mirza, Aabid Ali, Danish Ali Haider, Waleed Akbar.
Do all specimens of resected gall bladders need histopathological evaluation? a single centre retrospective study.
Pak J Surg Jan ;35(4):297-300.

Objective: The purpose of this study is to evaluate whether routine histopathology of gall bladder specimens removed for cholelithiasis, is needed every time or not, keeping in view the incidence of gall bladder cancer being diagnosed incidentally on histopathology for cholecystectomy done for cholelithiasis. Study design: Retrospective descriptive study. Sett ing and duration: General Surgery Department of Federal Government Polyclinic Hospital, Islamabad. 10 year data of histopathological reports of cholecystectomies was collected in February 2016. Material and Methods: A retrospective descriptive study was performed on all the histopathology reports of cholecystectomies, done over a period of 10 years in a single hospital. Results: Chronic cholecystitis with gall stones was the most common diagnosis with total 1,167 patients out of 1,298(89.9%). 3 out of 1,298 patients (0.3%) had adenocarcinoma of gall bladder, all pre-operatively and per-operatively had high index of suspicion for malignancy of gall bladder. Discussion: The diagnosis of incidental carcinoma gall bladder is very low in histopathological reports sent for resected gall bladder specimens for cholelithiasis. Conclusion: A selective policy is needed for sending gall bladder for histopathological examination, based on ultrasound and other imaging findings and per operative evaluation of gall bladder.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com