Gohar Latif Kalas, Naeem Akhtar, Abdul Hameed Khan, Anam Altaf.
Early post-operative pain in Laproscopic appendectomy versus open appendectomy.
Pak J Surg Jan ;35(3):201-4.

Objective: To compare post-operative pain scores in open and laparoscopic appendectomy Study design: Randomized Controlled trial (RCT) Study settings and duration: Study was conducted at department of surgery Pakistan Ordinnace Factory (POF) Hospital, Wah Cantt, for 6 months ( January 2018- June 2018) Material and methods: Sample size of 60 patients was calculated using WHO calculator. Non probability consecutive sampling was used. Patients were divided randomly into two groups using lottery method. Group-A underwent laparoscopic appendectomy while Group-B underwent open appendectomy. Ethical approval and consents form were taken patients were followed for measuring pain scores. Data was analyzed using SPSS version 23. T-Test and chi-square was applied. P value <=0.05 was considered significant. Results: Total 60 patients were included in study with 1:1 randomization (30 patients in each group). Th ere were 38(63%) male and 22(37%) female. Mean age of patients was 35.8 years 11.9 SD. Mean pain scores in laparoscopic appendectomy group 30(50%) were 0.60+-0.8 SD while mean pain scores in open appendectomy 30(50%) were 4.9+-1.2 SD (t= -15.392, df= 58, p=0.000). Laparoscopic and open appendectomy had significant association with age (p=0.05), DM (p=0.001), HTN (p=0.05), Pain distress (p=0.000) and Pain activity (p=0.03). Conclusion: Efficacy of laparoscopic appendectomy is better in terms of lower pain scores, pain distress and pain activity as compare to open appendectomy. Early diagnosis and treatment of appendicitis leads to better patient`s related outcome.

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