Abdul Qaiyoume Amini, Naveed Ali Khan, Khursheed Ahmed Samo, Amjad Siraj Memon.
Risk factors for acute idiopathic pancreatitis.
Pak J Surg Jan ;35(2):102-5.

Objective: To determine the risk factors for Acute Idiopathic Pancreatitis (AIP) in a tertiary care hospital of Karachi. Setting: Department of Surgery (Unit III), Dow University of Health Sciences, Civil Hospital, Karachi. Duration: From 13th January 2016 to 14th June 2018. Design: Cross sectional study. Material and Methods: All cases of abdominal pain diagnosed as acute pancreatitis on the basis of history, clinical examination and serum amylase levels (>3 times normal) were included in the study. Imaging studies (ultrasound, Computeds Tomography (CT) scan abdomen and Endoscopic retrograde cholango-pancreaticography (ERCP) were conducted in each case to confirm the diagnosis. A thorough assessment was done to determine the cause of acute pancreatitis including the radiological findings, previous history of abdominal trauma or surgery along with past medical history, drug history and socioeconomic activities (alcohol/smoking/ gutka/charas). Results: 70 cases of acute pancreatitis including 23 idiopathic cases, we found Gutka Chewing as the leading risk factor for acute idiopathic pancreatitis especially in young male patients with atypical presentation. Conclusion: Further studies are needed to determine the pathophysiological role of this increasingly important risk factor of acute pancreatitis.

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