Zahida Anwar, Zubaida Abid, Tahira Ghazenfer, Robina Usman, Rakhshanda Naheed, Aurangzeb Kamal, Mehreen Lashari, Jahanzaib Lashari.
Biochemical and Hematological Profile of Anemic and Non-Anemic Pregnant Women.
J Dow Uni Health Sci Jan ;14(2):54-9.

Objective:To determine the biochemical and hematological profile of pregnant women with and without anemia attending Sanderman Provincial Hospital, Quetta. Methods : This descriptive cross-sectional study was conducted among pregnant women aged ranged from 18 to 48 years attending the antenatal clinic for the first-time during February 2019 to August 2019. Hematological parameters like white blood cells (WBC), hemoglobin (Hb), hematocrit (HCT), Red blood cell distribution width (RDW), mean corpuscular hemoglobin concentration (MCHC), and mean corpuscular volume (MCV) were collected. Furthermore, biochemical parameters like serum ferritin and iron level, total iron-binding capacity (TIBC), Transferrin saturation (TfS), total bilirubin, direct bilirubin, and indirect bilirubin were also noted. Results : Of 357 patients, the mean Hb level was 10.27 +-1.53 g/dl. Majority of the pregnant were anemic, i.e. 248 (69.5%). Of these 248 anemic patients, mild anemia was found in 135 (54.4%), moderate anemia in 100 (40.3%) and severe anemia in 13 (5.2%) patients. A significantly lower level of Hb (p-value <0.001), WBC (p-value), HCT (p-value <0.001), MCHC (p-value <0.001), MCV (p-value <0.001), and RDW (p-value <0.001) was observed in patients with anemia as compared to non-anemic patients. Moreover, serum ferritin level (p-value 0.002), serum iron (p-value <0.001), and total bilirubin level (p-value <0.001) were found to be significantly lower in anemic patients than non-anemic patients. Conclusion : Anemia in pregnant women is associated with considerably low level of hematological and biochemical levels. Health providers should give attention to pregnant women with lower hematological and biochemical levels to prevent maternal and fetal complications.

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