Ahmad Z, Yaqoob N, Muzaffar S, Hussainy A S, Hasan S H.
Renal Carcinoid Tumor.
J Pak Med Assoc Jan ;53(10):491-2.

A 43 year old female presented to her local physician with a vague history of left flank pain, abdominal discomfort and haematuria. She was investigated and ultrasonography demonstrated a large mass in the left kidney. Left nephrectomy was performed. The specimen consisted of a kidney measuring 12.5 x 7.8 x 5.8cms. On sectioning, part of the kidney was replaced at the lower pole by a tan coloured circumscribed mass measuring 7.5 x 6.5 x 5.3 cms. Foci of necrosis and haemorrhage were also seen Histopathological examination showed a neoplasm composed of tubules and acini lined by cells with uniform round nuclei and pink cytoplasm. Occasional mitoses were seen. The sections were stained with a panel of monoclonal antibodies using the PAP technique. The tumour cells showed positivity for Chromogranin, Neuron Specific Enolase, Synaptophysin, Vimentin, Cytokeratins MNF and CAM 5.2. Sections from hilar blood vessels and ureteric margin of excision revealed no evidence of tumour. There was no pathological evidence of extra renal spread of the tumour. Invasion of the perirenal fat was not seen. Eight months after surgery, the patient is alive and well.

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